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Heart attacks don’t at all times look the identical — and a brand new examine from Mayo Clinic highlights the important thing variations between how they have an effect on women and men.
The commonest reason behind coronary heart assaults general is clogged arteries (atherosclerosis), however in folks underneath 65 — significantly girls — there are sometimes different elements at play.
Atherosclerosis is accountable for 75% of males’s coronary heart assaults, however solely 47% of women’s cardiac events, knowledge exhibits.
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Within the examine, which was revealed within the Journal of the American Faculty of Cardiology, researchers analyzed greater than 15 years of knowledge on 1,474 heart attacks.
They discovered that greater than half of coronary heart assaults in girls underneath age 65 had been brought on by “nontraditional elements.”

The commonest reason behind coronary heart assaults general is clogged arteries (atherosclerosis), however in folks underneath 65 — significantly girls — there are sometimes different elements at play. (iStock)
These included embolisms and spontaneous coronary artery dissection (SCAD), amongst different elements.
The researchers additionally discovered that the underlying causes of ladies’s coronary heart assaults had been usually neglected or misdiagnosed.
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SCAD — a uncommon however critical situation that happens when a tear develops throughout the coronary artery — is sort of six occasions extra widespread in girls in comparison with males.
It’s usually misdiagnosed as a typical coronary heart assault brought on by plaque buildup, which might lead to stents being placed unnecessarily, the researchers famous.

The analysis highlights the necessity to rethink how coronary heart assaults are approached, significantly in youthful girls. (iStock)
Individuals who skilled coronary heart assaults brought on by stressors like anemia or an infection had greater five-year mortality charges, the examine discovered.
“Recognizing and accurately diagnosing these nontraditional coronary heart assaults permits for extra acceptable care and higher long-term outcomes,” the discharge said.
Lower than 3% of coronary heart assaults had been “really unexplained.”
“When the foundation reason behind a coronary heart assault is misunderstood, it might probably result in therapies which might be much less efficient — and even dangerous.”
“This analysis shines a highlight on coronary heart assault causes which have traditionally been under-recognized, significantly in girls,” mentioned Claire Raphael, M.B.B.S., Ph.D., an interventional heart specialist at Mayo Clinic and first writer of the examine, in a press launch.
“When the foundation reason behind a coronary heart assault is misunderstood, it might probably result in therapies which might be much less efficient — and even dangerous.”
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Senior writer Rajiv Gulati, M.D., Ph.D., chair of the Division of Interventional Cardiology and Ischemic Coronary heart Illness at Mayo Clinic, mentioned the analysis highlights the necessity to rethink how coronary heart assaults are approached, significantly in younger women.
“Clinicians should sharpen their consciousness of situations like SCAD, embolism and stress-related triggers, and sufferers ought to advocate for solutions when one thing would not really feel proper,” he mentioned within the launch.
“Understanding why a coronary heart assault occurred is simply as essential as treating it,” Raphael added. “It could actually imply the distinction between restoration and recurrence.”

“It’s essential to acknowledge that not all coronary heart assaults are an identical or brought on by the identical occasions,” a heart specialist mentioned. (iStock)
Dr. Bradley Serwer, a Maryland-based heart specialist and chief medical officer at VitalSolution, an Ingenovis Well being firm that gives cardiovascular and anesthesiology services to hospitals nationwide, was not concerned within the examine however commented on the findings.
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“It’s essential to acknowledge that not all coronary heart assaults are an identical or brought on by the identical occasions,” he mentioned in an announcement supplied to Fox Information Digital. “Being younger, wholesome and feminine doesn’t assure immunity from coronary heart assault.”
The heart specialist emphasised the significance of listening to your physique and realizing that nobody is immune from a coronary heart assault.

“It is very important keep a wholesome way of life, train, keep away from smoking and know the standing of any power medical situations equivalent to diabetes, hypertension or excessive ldl cholesterol,” a physician suggested. (iStock)
“It is very important keep a healthy lifestyle, train, keep away from smoking and know the standing of any power medical situations equivalent to diabetes, hypertension or excessive ldl cholesterol,” he suggested.
“The best advocate is a well-informed affected person,” Serwer added. “It’s essential to concentrate on your medical historical past, medicines and particular cardiac threat elements.”
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Within the occasion of latest onset chest ache, shortness of breath or extreme exertional fatigue, the physician mentioned it’s important to hunt instant medical consideration.
“Don’t ignore the signs as a result of chances are you’ll be thought-about low threat for a coronary heart assault,” he mentioned.
“Being younger, wholesome and feminine doesn’t assure immunity from coronary heart assault.”
The examine does have some limitations, Serwer famous, together with an absence of ethnic variety.
“The analysis additionally didn’t account for severity of the underlying medical conditions,” he mentioned.
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Total, this examine serves as a reminder that there are a lot of completely different causes of coronary heart assaults, Serwer mentioned.
“We have to preserve an open thoughts when evaluating a youthful affected person with potential cardiac signs. There’s not a ‘one-size-fits-all’ strategy to treating coronary heart assaults within the younger.”